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Antioxidant metabolism regulates CD8(+) T memory stem cell formation and antitumor immunity
Adoptive T cell transfer (ACT) immunotherapy benefits from early differentiated stem cell memory T (Tscm) cells capable of persisting in the long term and generating potent antitumor effectors. Due to their paucity ex vivo, Tscm cells can be derived from naive precursors, but the molecular signals a...
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| Pubblicato in: | JCI Insight |
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| Autori principali: | , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237218/ https://ncbi.nlm.nih.gov/pubmed/30232291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122299 |
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