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Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice
BACKGROUND: Rho-associated kinases (ROCK1 and ROCK2) are important regulators of the actin cytoskeleton and endothelial nitric oxide synthase (eNOS). Because the phosphorylation of eukaryotic elongation factor-1 A1 (eEF1 A1) by ROCK2 is critical for eNOS expression, we hypothesized that this molecul...
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| Pubblicato in: | Circ J |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6235674/ https://ncbi.nlm.nih.gov/pubmed/29353861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1253/circj.CJ-17-0732 |
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