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Rho/Rho-Associated Coiled-Coil Forming Kinase Pathway as Therapeutic Targets for Statins in Atherosclerosis

Significance: The 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors or statins are important therapeutic agents for lowering serum cholesterol levels. However, recent studies suggest that statins may exert atheroprotective effects beyond cholesterol lowering. These so-called “pleiotropic effe...

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Autores principales: Sawada, Naoki, Liao, James K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934442/
https://ncbi.nlm.nih.gov/pubmed/23919640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5524
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