Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway

BACKGROUND: Melanomas are highly malignant and have high metastatic potential; hence, there is a need for new therapeutic strategies to prevent cell metastasis. In the present study, we investigated whether statins inhibit tumor cell migration, invasion, adhesion, and metastasis in the B16BL6 mouse...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kidera, Yasuhiro, Tsubaki, Masanobu, Yamazoe, Yuzuru, Shoji, Kaori, Nakamura, Haruyuki, Ogaki, Mitsuhiko, Satou, Takao, Itoh, Tatsuki, Isozaki, Misako, Kaneko, Junichi, Tanimori, Yoshihiro, Yanae, Masashi, Nishida, Shozo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949822/
https://ncbi.nlm.nih.gov/pubmed/20843370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-127
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