Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

Por Yanae, Masashi, Tsubaki, Masanobu, Satou, Takao, Itoh, Tatsuki, Imano, Motohiro, Yamazoe, Yuzuru, Nishida, Shozo
Publicado em 2011

Mangiferin suppresses CIA by suppressing the expression of TNF-α, IL-6, IL-1β, and RANKL through inhibiting the activation of NF-κB and ERK1/2

Por Tsubaki, Masanobu, Takeda, Tomoya, Kino, Toshiki, Itoh, Tatsuki, Imano, Motohiro, Tanabe, Genzo, Muraoka, Osamu, Satou, Takao, Nishida, Shozo
Publicado no Am J Transl Res (2015)

Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells

Por Tsubaki, Masanobu, Takeda, Tomoya, Kino, Toshiki, Sakai, Kazuko, Itoh, Tatsuki, Imano, Motohiro, Nakayama, Takashi, Nishio, Kazuto, Satou, Takao, Nishida, Shozo
Publicado no Oncotarget (2017)

Statins improve survival by inhibiting spontaneous metastasis and tumor growth in a mouse melanoma model

Por Tsubaki, Masanobu, Takeda, Tomoya, Kino, Toshiki, Obata, Naoya, Itoh, Tatsuki, Imano, Motohiro, Mashimo, Kenji, Fujiwara, Daichiro, Sakaguchi, Katsuhiko, Satou, Takao, Nishida, Shozo
Publicado no Am J Cancer Res (2015)

Bisphosphonates and statins inhibit expression and secretion of MIP-1α via suppression of Ras/MEK/ERK/AML-1A and Ras/PI3K/Akt/AML-1A pathways

Por Tsubaki, Masanobu, Takeda, Tomoya, Sakamoto, Kotaro, Shimaoka, Hirotaka, Fujita, Arisa, Itoh, Tatsuki, Imano, Motohiro, Mashimo, Kenji, Fujiwara, Daiichiro, Sakaguchi, Katsuhiko, Satou, Takao, Nishida, Shozo
Publicado no Am J Cancer Res (2014)

Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway

Por Kidera, Yasuhiro, Tsubaki, Masanobu, Yamazoe, Yuzuru, Shoji, Kaori, Nakamura, Haruyuki, Ogaki, Mitsuhiko, Satou, Takao, Itoh, Tatsuki, Isozaki, Misako, Kaneko, Junichi, Tanimori, Yoshihiro, Yanae, Masashi, Nishida, Shozo
Publicado em 2010

Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation

Por Tsubaki, Masanobu, Komai, Makiko, Itoh, Tatsuki, Imano, Motohiro, Sakamoto, Kotaro, Shimaoka, Hirotaka, Takeda, Tomoya, Ogawa, Naoki, Mashimo, Kenji, Fujiwara, Daiichiro, Mukai, Junji, Sakaguchi, Katsuhiko, Satou, Takao, Nishida, Shozo
Publicado em 2014

PKN3 is the major regulator of angiogenesis and tumor metastasis in mice

Por Mukai, Hideyuki, Muramatsu, Aiko, Mashud, Rana, Kubouchi, Koji, Tsujimoto, Sho, Hongu, Tsunaki, Kanaho, Yasunori, Tsubaki, Masanobu, Nishida, Shozo, Shioi, Go, Danno, Sally, Mehruba, Mona, Satoh, Ryosuke, Sugiura, Reiko
Publicado no Sci Rep (2016)

Increased risk of SSEs in bone-only metastatic breast cancer patients treated with zoledronic acid

Por Yanae, Masashi, Fujimoto, Shinichiro, Tane, Kaori, Tanioka, Maki, Fujiwara, Kimiko, Tsubaki, Masanobu, Yamazoe, Yuzuru, Morishima, Yoshiyuki, Chiba, Yasutaka, Takao, Shintaro, Komoike, Yoshifumi, Tsurutani, Junji, Nakagawa, Kazuhiko, Nishida, Shozo
Publicado no J Bone Oncol (2017)

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines

Por Tsubaki, Masanobu, Komai, Makiko, Fujimoto, Shin-ichiro, Itoh, Tatsuki, Imano, Motohiro, Sakamoto, Kotaro, Shimaoka, Hirotaka, Takeda, Tomoya, Ogawa, Naoki, Mashimo, Kenji, Fujiwara, Daiichiro, Mukai, Junji, Sakaguchi, Katsuhiko, Satou, Takao, Nishida, Shozo
Publicado em 2013