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Rho-associated Coiled-coil Forming Kinase (ROCK): a potential target for the treatment of atherosclerosis and vascular disease

The Rho/Rho-associated coiled-coil forming kinases (ROCKs) are important regulators of the actin cytoskeleton. Because changes in the actin cytoskeleton underlie vascular contractility and remodeling, inflammatory cell recruitment, and cellular proliferation, it is likely that the Rho/ROCK pathway w...

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Detalhes bibliográficos
Main Authors: Zhou, Qian, Gensch, Christoph, Liao, James K
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080120/
https://ncbi.nlm.nih.gov/pubmed/21242007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2010.12.006
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