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Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms
Rho-kinase is a serine threonine kinase that increases vasomotor tone via its effects on both endothelium and smooth muscle. Rho-kinase inhibition reduces cerebral infarct size in wild type, but not endothelial nitric oxide synthase deficient (eNOS(−/−)) mice. The mechanism may be related to Rho-kin...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614438/ https://ncbi.nlm.nih.gov/pubmed/17033691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600406 |
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