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Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms

Rho-kinase is a serine threonine kinase that increases vasomotor tone via its effects on both endothelium and smooth muscle. Rho-kinase inhibition reduces cerebral infarct size in wild type, but not endothelial nitric oxide synthase deficient (eNOS(−/−)) mice. The mechanism may be related to Rho-kin...

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Detaylı Bibliyografya
Asıl Yazarlar: Shin, Hwa Kyoung, Salomone, Salvatore, Potts, E Michelle, Lee, Sae-Won, Millican, Eric, Noma, Kensuke, Huang, Paul L, Boas, David A, Liao, James K, Moskowitz, Michael A, Ayata, Cenk
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614438/
https://ncbi.nlm.nih.gov/pubmed/17033691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600406
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