Cryo-EM structure of the mechanically activated ion channel OSCA1.2

Mechanically activated ion channels underlie touch, hearing, shear-stress sensing, and response to turgor pressure. OSCA/TMEM63s are a newly-identified family of eukaryotic mechanically activated ion channels opened by membrane tension. The structural underpinnings of OSCA/TMEM63 function are not ex...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Jojoa-Cruz, Sebastian, Saotome, Kei, Murthy, Swetha E, Tsui, Che Chun Alex, Sansom, Mark SP, Patapoutian, Ardem, Ward, Andrew B
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Structural Biology and Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235563/
https://ncbi.nlm.nih.gov/pubmed/30382939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41845
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