Discovery of a Small Molecule to Increase Cardiomyocytes and Protect the Heart After Ischemic Injury

Accumulating data suggest that new cardiomyocytes in adults are generated from existing cardiomyocytes throughout life. To enhance the endogenous cardiac regeneration, we performed chemical screenings to identify compounds that activate pro-proliferative YES-associated protein and transcriptional en...

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Dades bibliogràfiques
Publicat a:JACC Basic Transl Sci
Autors principals: Hara, Hironori, Takeda, Norifumi, Kondo, Masaki, Kubota, Mio, Saito, Tatsuo, Maruyama, Junichi, Fujiwara, Takayuki, Maemura, Sonoko, Ito, Masamichi, Naito, Atsuhiko T., Harada, Mutsuo, Toko, Haruhiro, Nomura, Seitaro, Kumagai, Hidetoshi, Ikeda, Yuichi, Ueno, Hiroo, Takimoto, Eiki, Akazawa, Hiroshi, Morita, Hiroyuki, Aburatani, Hiroyuki, Hata, Yutaka, Uchiyama, Masanobu, Komuro, Issei
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
PRECLINICAL RESEARCH
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234526/
https://ncbi.nlm.nih.gov/pubmed/30456335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.07.005
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