Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

Pressure overload induces a transition from cardiac hypertrophy to heart failure, but its underlying mechanisms remain elusive. Here we reconstruct a trajectory of cardiomyocyte remodeling and clarify distinct cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hy...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nomura, Seitaro, Satoh, Masahiro, Fujita, Takanori, Higo, Tomoaki, Sumida, Tomokazu, Ko, Toshiyuki, Yamaguchi, Toshihiro, Tobita, Takashige, Naito, Atsuhiko T., Ito, Masamichi, Fujita, Kanna, Harada, Mutsuo, Toko, Haruhiro, Kobayashi, Yoshio, Ito, Kaoru, Takimoto, Eiki, Akazawa, Hiroshi, Morita, Hiroyuki, Aburatani, Hiroyuki, Komuro, Issei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207673/
https://ncbi.nlm.nih.gov/pubmed/30375404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06639-7
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