Discovery of a Small Molecule to Increase Cardiomyocytes and Protect the Heart After Ischemic Injury

Accumulating data suggest that new cardiomyocytes in adults are generated from existing cardiomyocytes throughout life. To enhance the endogenous cardiac regeneration, we performed chemical screenings to identify compounds that activate pro-proliferative YES-associated protein and transcriptional en...

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Bibliografiska uppgifter
I publikationen:JACC Basic Transl Sci
Huvudupphovsmän: Hara, Hironori, Takeda, Norifumi, Kondo, Masaki, Kubota, Mio, Saito, Tatsuo, Maruyama, Junichi, Fujiwara, Takayuki, Maemura, Sonoko, Ito, Masamichi, Naito, Atsuhiko T., Harada, Mutsuo, Toko, Haruhiro, Nomura, Seitaro, Kumagai, Hidetoshi, Ikeda, Yuichi, Ueno, Hiroo, Takimoto, Eiki, Akazawa, Hiroshi, Morita, Hiroyuki, Aburatani, Hiroyuki, Hata, Yutaka, Uchiyama, Masanobu, Komuro, Issei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2018
Ämnen:
PRECLINICAL RESEARCH
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234526/
https://ncbi.nlm.nih.gov/pubmed/30456335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.07.005
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