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H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells

During the aging process, bone marrow mesenchymal stem cells (BMSCs) exhibit declined osteogenesis accompanied by excess adipogenesis, which will lead to osteoporosis. Here, we report that the H3 lysine 36 trimethylation (H3K36me3), catalyzed by histone methyltransferase SET-domain-containing 2 (SET...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Wang, Lijun, Niu, Ningning, Li, Li, Shao, Rui, Ouyang, Huiling, Zou, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233919/
https://ncbi.nlm.nih.gov/pubmed/30422989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006522
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