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H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells

During the aging process, bone marrow mesenchymal stem cells (BMSCs) exhibit declined osteogenesis accompanied by excess adipogenesis, which will lead to osteoporosis. Here, we report that the H3 lysine 36 trimethylation (H3K36me3), catalyzed by histone methyltransferase SET-domain-containing 2 (SET...

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Bibliografiska uppgifter
I publikationen:PLoS Biol
Huvudupphovsmän: Wang, Lijun, Niu, Ningning, Li, Li, Shao, Rui, Ouyang, Huiling, Zou, Weiguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233919/
https://ncbi.nlm.nih.gov/pubmed/30422989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006522
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