H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells

During the aging process, bone marrow mesenchymal stem cells (BMSCs) exhibit declined osteogenesis accompanied by excess adipogenesis, which will lead to osteoporosis. Here, we report that the H3 lysine 36 trimethylation (H3K36me3), catalyzed by histone methyltransferase SET-domain-containing 2 (SET...

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Detaylı Bibliyografya
Yayımlandı:PLoS Biol
Asıl Yazarlar: Wang, Lijun, Niu, Ningning, Li, Li, Shao, Rui, Ouyang, Huiling, Zou, Weiguo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233919/
https://ncbi.nlm.nih.gov/pubmed/30422989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006522
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