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H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells
During the aging process, bone marrow mesenchymal stem cells (BMSCs) exhibit declined osteogenesis accompanied by excess adipogenesis, which will lead to osteoporosis. Here, we report that the H3 lysine 36 trimethylation (H3K36me3), catalyzed by histone methyltransferase SET-domain-containing 2 (SET...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | PLoS Biol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6233919/ https://ncbi.nlm.nih.gov/pubmed/30422989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006522 |
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