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Bromodomain and Extra-terminal (BET) Protein Inhibitors Suppress Chondrocyte Differentiation and Restrain Bone Growth

Small molecule inhibitors for bromodomain and extra-terminal (BET) proteins have recently emerged as potential therapeutic agents in clinical trials for various cancers. However, to date, it is unknown whether these inhibitors have side effects on bone structures. Here, we report that inhibition of...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Niu, Ningning, Shao, Rui, Yan, Guang, Zou, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207175/
https://ncbi.nlm.nih.gov/pubmed/27821592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749697
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