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Synthetic studies of microtubule stabilizing agent peloruside A: an asymmetric synthesis of C(10)–C(24) segment
An asymmetric synthesis of the C(10)–C(24) fragment of the potent antitumor macrolide, peloruside A is described. All three stereogenic centers have been enantioselectively constructed utilizing Evans alkylation, Brown asymmetric allylboration, and a substrate controlled epoxide formation. Other key...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6233903/ https://ncbi.nlm.nih.gov/pubmed/30443085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2003.08.023 |
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