Peloruside A is a microtubule-stabilizing agent with exceptional anti-migratory properties in human endothelial cells

Peloruside A is a novel antimitotic drug originally isolated from the marine sponge Mycale hentschieli. Previous studies showed that peloruside A stabilizes microtubules by binding to a site on tubulin distinct from paclitaxel, another microtubule stabilizing drug. Peloruside A blocks mitosis, but l...

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Publicado en:Oncoscience
Autores principales: Ganguly, Anutosh, Cabral, Fernando, Yang, Hailing, Patel, Kamala D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506362/
https://ncbi.nlm.nih.gov/pubmed/26244166
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