Inhibition of Cell Migration and Cell Division Correlates with Distinct Effects of Microtubule Inhibiting Drugs

Drugs that target microtubules are thought to inhibit cell division and cell migration by suppressing dynamic instability, a “search and capture” behavior that allows microtubules to probe their environment. Here, we report that subtoxic drug concentrations are sufficient to inhibit plus-end microtu...

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Bibliographic Details
Main Authors: Yang, Hailing, Ganguly, Anutosh, Cabral, Fernando
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952225/
https://ncbi.nlm.nih.gov/pubmed/20696757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.160820
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