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Class III β-Tubulin Counteracts the Ability of Paclitaxel to Inhibit Cell Migration

Class III β-tubulin (β3) is associated with tumor aggressiveness, resistance to therapy, and patient relapse. To elucidate its action, we tested β3's effect on cell migration. Expression of β3 in HeLa and MCF-7 did not alter the intrinsic rate of cell migration, but it prevented the inhibition...

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Detalhes bibliográficos
Main Authors: Ganguly, Anutosh, Yang, Hailing, Cabral, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248193/
https://ncbi.nlm.nih.gov/pubmed/21576762
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