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Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology

Sirtuins are NAD(+)-dependent protein deacylases/ADP-ribosyltransferases that have emerged as candidate targets for new therapeutics to treat metabolic disorders and other diseases, including cancer. The sirtuin SIRT5 resides primarily in the mitochondrial matrix, and catalyzes the removal of negati...

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Podrobná bibliografie
Vydáno v:Crit Rev Biochem Mol Biol
Hlavní autoři: Kumar, Surinder, Lombard, David B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233320/
https://ncbi.nlm.nih.gov/pubmed/29637793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1458071
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