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Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology
Sirtuins are NAD(+)-dependent protein deacylases/ADP-ribosyltransferases that have emerged as candidate targets for new therapeutics to treat metabolic disorders and other diseases, including cancer. The sirtuin SIRT5 resides primarily in the mitochondrial matrix, and catalyzes the removal of negati...
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| Publié dans: | Crit Rev Biochem Mol Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6233320/ https://ncbi.nlm.nih.gov/pubmed/29637793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1458071 |
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