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Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology

Sirtuins are NAD(+)-dependent protein deacylases/ADP-ribosyltransferases that have emerged as candidate targets for new therapeutics to treat metabolic disorders and other diseases, including cancer. The sirtuin SIRT5 resides primarily in the mitochondrial matrix, and catalyzes the removal of negati...

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書目詳細資料
發表在:Crit Rev Biochem Mol Biol
Main Authors: Kumar, Surinder, Lombard, David B.
格式: Artigo
語言:Inglês
出版: 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233320/
https://ncbi.nlm.nih.gov/pubmed/29637793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1458071
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