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Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology

Sirtuins are NAD(+)-dependent protein deacylases/ADP-ribosyltransferases that have emerged as candidate targets for new therapeutics to treat metabolic disorders and other diseases, including cancer. The sirtuin SIRT5 resides primarily in the mitochondrial matrix, and catalyzes the removal of negati...

詳細記述

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書誌詳細
出版年:Crit Rev Biochem Mol Biol
主要な著者: Kumar, Surinder, Lombard, David B.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233320/
https://ncbi.nlm.nih.gov/pubmed/29637793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1458071
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