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Novel Roles for the Sirtuin Deacylase SIRT5 in Normal Physiology and in Cancer
Sirtuins are NAD+-dependent deacylases that regulate diverse cellular processes such as metabolic homeostasis and genomic integrity. Mammals possess seven sirtuin family members, SIRT1-SIRT7, that display diverse subcellular localization patterns, catalytic activities, protein targets, and biologica...
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| Udgivet i: | Innov Aging |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7741316/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.2652 |
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