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Generation and purification of catalytically active recombinant SIRT5 protein
Sirtuin-family deacylases promote health and longevity in mammals. The sirtuin SIRT5 localizes predominantly to the mitochondrial matrix. SIRT5 preferentially removes negatively charged modifications from its target lysines: succinylation, malonylation, and glutarylation. It regulates protein substr...
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| Publicado en: | Methods Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4890613/ https://ncbi.nlm.nih.gov/pubmed/27246219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3667-0_16 |
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