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Role of oligouridylation in normal metabolism and regulated degradation of mammalian histone mRNAs
Metazoan replication-dependent histone mRNAs are the only known cellular mRNAs that are not polyadenylated. Histone mRNAs are present in large amounts only in S-phase cells, and their levels are coordinately regulated with the rate of DNA replication. In mammals, the stemloop at the 3′ end of histon...
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| Опубликовано в: : | Philos Trans R Soc Lond B Biol Sci |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Royal Society
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6232589/ https://ncbi.nlm.nih.gov/pubmed/30397106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0170 |
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