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Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

The canonical histone proteins are encoded by replication-dependent genes and must rapidly reach high levels of expression during S phase. In metazoans the genes that encode these proteins produce mRNAs that, instead of being polyadenylated, contain a unique 3' end structure. By contrast, the s...

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Autors principals: Marzluff, William F., Wagner, Eric J., Duronio, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715827/
https://ncbi.nlm.nih.gov/pubmed/18927579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2438
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