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Birth and Death of Histone mRNAs

In metazoans, histone mRNAs are not polyadenylated but end in a conserved stem-loop. Stem-loop binding protein (SLBP) binds to the stem-loop and is required for all steps in histone mRNA metabolism. The genes for the five histone proteins are linked. A histone locus body (HLB) forms at each histone...

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Bibliographic Details
Published in:Trends Genet
Main Authors: Marzluff, William F., Koreski, Kaitlin P.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645032/
https://ncbi.nlm.nih.gov/pubmed/28867047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2017.07.014
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