Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin

Several bacterial pathogens produce nucleotidyl cyclase toxins to manipulate eukaryotic host cells. Inside host cells they are activated by endogenous cofactors to produce high levels of cyclic nucleotides (cNMPs). The ExoY toxin from Pseudomonas aeruginosa (PaExoY) and the ExoY-like module (VnExoY)...

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Vydáno v:PLoS One
Hlavní autoři: Raoux-Barbot, Dorothée, Belyy, Alexander, Worpenberg, Lina, Montluc, Sabrina, Deville, Celia, Henriot, Véronique, Velours, Christophe, Ladant, Daniel, Renault, Louis, Mechold, Undine
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231621/
https://ncbi.nlm.nih.gov/pubmed/30419035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206133
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