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The extreme C terminus of the Pseudomonas aeruginosa effector ExoY is crucial for binding to its eukaryotic activator, F-actin
Bacterial nucleotidyl cyclase toxins are potent virulence factors that upon entry into eukaryotic cells are stimulated by endogenous cofactors to catalyze the production of large amounts of 3′5′-cyclic nucleoside monophosphates. The activity of the effector ExoY from Pseudomonas aeruginosa is stimul...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314138/ https://ncbi.nlm.nih.gov/pubmed/30377256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003784 |
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