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ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation

In addition to the well known second messengers cAMP and cGMP, mammalian cells contain the cyclic pyrimidine nucleotides cCMP and cUMP. Soluble guanylyl cyclase and soluble adenylyl cyclase produce all four cNMPs. Several bacterial toxins exploit mammalian cyclic nucleotide signaling. The type III s...

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Bibliografiske detaljer
Udgivet i:Biochem Biophys Res Commun
Main Authors: Beckert, Urike, Wolter, Sabine, Hartwig, Christina, Bähre, Heike, Kaever, Volkhard, Ladant, Daniel, Frank, Dara W., Seifert, Roland
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764875/
https://ncbi.nlm.nih.gov/pubmed/24971548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.06.088
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