ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation

In addition to the well known second messengers cAMP and cGMP, mammalian cells contain the cyclic pyrimidine nucleotides cCMP and cUMP. Soluble guanylyl cyclase and soluble adenylyl cyclase produce all four cNMPs. Several bacterial toxins exploit mammalian cyclic nucleotide signaling. The type III s...

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Publicado en:Biochem Biophys Res Commun
Main Authors: Beckert, Urike, Wolter, Sabine, Hartwig, Christina, Bähre, Heike, Kaever, Volkhard, Ladant, Daniel, Frank, Dara W., Seifert, Roland
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764875/
https://ncbi.nlm.nih.gov/pubmed/24971548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.06.088
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