Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

The nucleotidyl cyclase toxin ExoY is one of the virulence factors injected by the Pseudomonas aeruginosa type III secretion system into host cells. Inside cells, it is activated by an unknown eukaryotic cofactor to synthesize various cyclic nucleotide monophosphates. ExoY-like adenylate cyclases ar...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Belyy, Alexander, Raoux-Barbot, Dorothée, Saveanu, Cosmin, Namane, Abdelkader, Ogryzko, Vasily, Worpenberg, Lina, David, Violaine, Henriot, Veronique, Fellous, Souad, Merrifield, Christien, Assayag, Elodie, Ladant, Daniel, Renault, Louis, Mechold, Undine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150216/
https://ncbi.nlm.nih.gov/pubmed/27917880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13582
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