The extreme C terminus of the Pseudomonas aeruginosa effector ExoY is crucial for binding to its eukaryotic activator, F-actin

Bacterial nucleotidyl cyclase toxins are potent virulence factors that upon entry into eukaryotic cells are stimulated by endogenous cofactors to catalyze the production of large amounts of 3′5′-cyclic nucleoside monophosphates. The activity of the effector ExoY from Pseudomonas aeruginosa is stimul...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Belyy, Alexander, Santecchia, Ignacio, Renault, Louis, Bourigault, Blandine, Ladant, Daniel, Mechold, Undine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Enzymology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314138/
https://ncbi.nlm.nih.gov/pubmed/30377256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003784
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