Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin

Several bacterial pathogens produce nucleotidyl cyclase toxins to manipulate eukaryotic host cells. Inside host cells they are activated by endogenous cofactors to produce high levels of cyclic nucleotides (cNMPs). The ExoY toxin from Pseudomonas aeruginosa (PaExoY) and the ExoY-like module (VnExoY)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Raoux-Barbot, Dorothée, Belyy, Alexander, Worpenberg, Lina, Montluc, Sabrina, Deville, Celia, Henriot, Véronique, Velours, Christophe, Ladant, Daniel, Renault, Louis, Mechold, Undine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231621/
https://ncbi.nlm.nih.gov/pubmed/30419035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206133
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