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Variability of Complement Response toward Preclinical and Clinical Nanocarriers in the General Population

Opsonization (coating) of nanoparticles with complement C3 component is an important mechanism that triggers immune clearance and downstream anaphylactic and proinflammatory responses. The variability of complement C3 binding to nanoparticles in the general population has not been studied. We examin...

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Bibliografski detalji
Izdano u:Bioconjug Chem
Glavni autori: Benasutti, Halli, Wang, Guankui, Vu, Vivian P., Scheinman, Robert, Groman, Ernest, Saba, Laura, Simberg, Dmitri
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231230/
https://ncbi.nlm.nih.gov/pubmed/29090582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00496
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