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Variability of Complement Response toward Preclinical and Clinical Nanocarriers in the General Population

Opsonization (coating) of nanoparticles with complement C3 component is an important mechanism that triggers immune clearance and downstream anaphylactic and proinflammatory responses. The variability of complement C3 binding to nanoparticles in the general population has not been studied. We examin...

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Библиографические подробности
Опубликовано в: :Bioconjug Chem
Главные авторы: Benasutti, Halli, Wang, Guankui, Vu, Vivian P., Scheinman, Robert, Groman, Ernest, Saba, Laura, Simberg, Dmitri
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231230/
https://ncbi.nlm.nih.gov/pubmed/29090582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00496
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