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Variability of Complement Response toward Preclinical and Clinical Nanocarriers in the General Population

Opsonization (coating) of nanoparticles with complement C3 component is an important mechanism that triggers immune clearance and downstream anaphylactic and proinflammatory responses. The variability of complement C3 binding to nanoparticles in the general population has not been studied. We examin...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Benasutti, Halli, Wang, Guankui, Vu, Vivian P., Scheinman, Robert, Groman, Ernest, Saba, Laura, Simberg, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231230/
https://ncbi.nlm.nih.gov/pubmed/29090582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00496
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