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Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro

BACKGROUND: The mechanism of chemoresistance remains unknown. Here, we investigated if glucose transporter-1 (GLUT-1) and PI3K/Akt pathways are associated with the sensitivity to cisplatin in Hep-2 laryngeal carcinoma cells and whether the inhibition of GLUT-1 and the PI3K/Akt pathways enhances the...

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Bibliografiska uppgifter
I publikationen:Onco Targets Ther
Huvudupphovsmän: Jiang, Tao, Zhou, Min-Li, Fan, Jun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6228052/
https://ncbi.nlm.nih.gov/pubmed/30464533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S176818
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