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Co-Inhibition of GLUT-1 Expression and the PI3K/Akt Signaling Pathway to Enhance the Radiosensitivity of Laryngeal Carcinoma Xenografts In Vivo

In the present study, we investigated the role of GLUT-1 and PI3K/Akt signaling in radioresistance of laryngeal carcinoma xenografts. Volume, weight, radiosensitization, and the rate of inhibition of tumor growth in the xenografts were evaluated in different groups. Apoptosis was evaluated by TUNEL...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Luo, Xing-Mei, Xu, Bin, Zhou, Min-Li, Bao, Yang-Yang, Zhou, Shui-Hong, Fan, Jun, Lu, Zhong-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658010/
https://ncbi.nlm.nih.gov/pubmed/26600164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143306
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