Co-Inhibition of GLUT-1 Expression and the PI3K/Akt Signaling Pathway to Enhance the Radiosensitivity of Laryngeal Carcinoma Xenografts In Vivo

In the present study, we investigated the role of GLUT-1 and PI3K/Akt signaling in radioresistance of laryngeal carcinoma xenografts. Volume, weight, radiosensitization, and the rate of inhibition of tumor growth in the xenografts were evaluated in different groups. Apoptosis was evaluated by TUNEL...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Luo, Xing-Mei, Xu, Bin, Zhou, Min-Li, Bao, Yang-Yang, Zhou, Shui-Hong, Fan, Jun, Lu, Zhong-Jie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658010/
https://ncbi.nlm.nih.gov/pubmed/26600164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143306
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