Apigenin suppresses GLUT-1 and p-AKT expression to enhance the chemosensitivity to cisplatin of laryngeal carcinoma Hep-2 cells: an in vitro study

Glucose transporter-1 (GLUT-1) and PI3K/Akt are known to be closely involved in resistance to chemotherapy. Co-targeted therapy reducing GLUT-1 expression and PI3K/Akt pathway activity may overcome the chemoresistance of human cancers. Apigenin may inhibit the expression of GLUT-1 and the PI3K/Akt p...

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Main Authors: Xu, Ying-Ying, Wu, Ting-Ting, Zhou, Shui-Hong, Bao, Yang-Yang, Wang, Qin-Ying, Fan, Jun, Huang, Ya-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129005/
https://ncbi.nlm.nih.gov/pubmed/25120770
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