BEZ235 enhances chemosensitivity of paclitaxel in hepatocellular carcinoma through inhibiting the PI3K/Akt/mTOR pathway

Desensitization of hepatocellular carcinoma (HCC) to paclitaxel chemotherapy is a major deterrent to successful treatment of the cancer. Abnormal activation of the PI3K/Akt/mTOR, pathway is a common outcome of chemotherapy for HCC. Therefore, we investigated whether BEZ235, a dual PI3K and mTOR inhi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Transl Res
Egile Nagusiak: Liu, Xueke, Xie, Chunmei, Li, Amin, Zhang, Yinci, Liu, Xinkuang, Zhou, Shuping, Shen, Jing, Huo, Zhen, Cao, Weiya, Ma, Yongfang, Xu, Ruyue, Xing, Yingru, Xie, Yinghai, Cai, Shuyu, Tang, Xiaolong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: e-Century Publishing Corporation 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943462/
https://ncbi.nlm.nih.gov/pubmed/31934276
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak