BEZ235 Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib by Inhibiting PI3K/AKT/mTOR and Inducing Autophagy

Acquired resistance of hepatocellular carcinoma (HCC) to sorafenib (SFB) is the main reason for the failure of SFB treatment of the cancer. Abnormal activation of the PI3K/AKT/mTOR pathway is important in the acquired resistance of SFB. Therefore, we investigated whether BEZ235 (BEZ) could reverse a...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Biomed Res Int
Главные авторы: Cao, Weiya, Liu, Xueke, Zhang, Yinci, Li, Amin, Xie, Yinghai, Zhou, Shuping, Song, Li, Xu, Ruyue, Ma, Yongfang, Cai, Shiyu, Tang, Xiaolong
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2021
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079203/
https://ncbi.nlm.nih.gov/pubmed/33987439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5556306
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы