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Combination of PI3K/Akt Pathway Inhibition and Plk1 Depletion Can Enhance Chemosensitivity to Gemcitabine in Pancreatic Carcinoma

The prognosis of pancreatic cancer (PC) remains pessimistic because of the difficulty in early diagnosis as well as the little advance in chemotherapy. Although being the first-line chemotherapy drug for PC at present, gemcitabine still has some disadvantages, such as low drug sensitivity and signif...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Mao, Yonghuan, Xi, Ling, Li, Quan, Wang, Sheng, Cai, Zeling, Zhang, Xinhua, Yu, Chunzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052177/
https://ncbi.nlm.nih.gov/pubmed/29753186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.04.011
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