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Regulation of cell apoptosis and proliferation in pancreatic cancer through PI3K/Akt pathway via Polo-like kinase 1

Pancreatic cancer has a poor prognosis. It is reported that the PI3K/Akt pathway is activated in many cancers, and inhibition of the PI3K/Akt pathway can induce cell apoptosis in most cancers. Polo-like kinase 1 (Plk1) is also overexpressed in most malignancies, and it controls multiple aspects of m...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: MAO, YONGHUAN, XI, LING, LI, QUAN, CAI, ZELING, LAI, YIMEI, ZHANG, XINHUA, YU, CHUNZHAO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899032/
https://ncbi.nlm.nih.gov/pubmed/27220401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4820
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