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Synergistic effects of BET and MEK inhibitors promote regression of anaplastic thyroid tumors
Anaplastic thyroid cancer (ATC) is an aggressive malignancy with limited options for treatment. Targeting epigenetic modifications via interfering with the interaction between the bromodomain and extra-terminal domain (BET) proteins and acetylated histones by using BET inhibitors (e.g., JQ1) has sho...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6226043/ https://ncbi.nlm.nih.gov/pubmed/30459933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26253 |
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