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Synergistic effects of BET and MEK inhibitors promote regression of anaplastic thyroid tumors

Anaplastic thyroid cancer (ATC) is an aggressive malignancy with limited options for treatment. Targeting epigenetic modifications via interfering with the interaction between the bromodomain and extra-terminal domain (BET) proteins and acetylated histones by using BET inhibitors (e.g., JQ1) has sho...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Zhu, Xuguang, Holmsen, Erik, Park, Sunmi, Willingham, Mark C., Qi, Jun, Cheng, Sheue-yann
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226043/
https://ncbi.nlm.nih.gov/pubmed/30459933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26253
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