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Potentiated Anti-tumor Effects of BETi by MEKi in Anaplastic Thyroid Cancer
Anaplastic thyroid cancer (ATC) is an aggressive malignancy with limited treatment options. We explored novel treatment modalities by targeting epigenetic modifications using inhibitors of BET (e.g. BRD4) activity. We evaluated the efficacy in the treatment of ATC of a novel BET inhibitor, PLX51107...
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| Опубликовано в: : | Endocr Relat Cancer |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6938575/ https://ncbi.nlm.nih.gov/pubmed/31272080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-19-0107 |
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