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Targeting MYC as a Therapeutic Intervention for Anaplastic Thyroid Cancer
CONTEXT: Recent studies showed that transcription of the MYC gene is driven by the interaction of bromodomain and extraterminal domain (BET) proteins with acetylated histones on chromatin. JQ1, a potent inhibitor that effectively disrupts the interaction of BET proteins with acetylated histones, pre...
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| Izdano u: | J Clin Endocrinol Metab |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Endocrine Society
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5505205/ https://ncbi.nlm.nih.gov/pubmed/28368473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3771 |
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