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Potentiated Anti-tumor Effects of BETi by MEKi in Anaplastic Thyroid Cancer
Anaplastic thyroid cancer (ATC) is an aggressive malignancy with limited treatment options. We explored novel treatment modalities by targeting epigenetic modifications using inhibitors of BET (e.g. BRD4) activity. We evaluated the efficacy in the treatment of ATC of a novel BET inhibitor, PLX51107...
Gardado en:
| Publicado en: | Endocr Relat Cancer |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6938575/ https://ncbi.nlm.nih.gov/pubmed/31272080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-19-0107 |
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