TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation

The Warburg effect is a prominent metabolic feature associated with neoplastic diseases; however, the underlying mechanism remains incompletely understood. TAp73, a structural homolog of the tumor suppressor p53, is frequently overexpressed in human tumors, indicating a proliferative advantage that...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Li, Le, Li, Lijia, Li, Wei, Chen, Taiqi, Bin Zou, Zhao, Lina, Wang, Huili, Wang, Xueying, Xu, Lina, Liu, Xiaohui, Wang, Dong, Li, Bo, Mak, Tak W., Du, Wenjing, Yang, Xiaolu, Jiang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224601/
https://ncbi.nlm.nih.gov/pubmed/30409970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07127-8
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