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A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation
The pentose phosphate pathway (PPP) provides ribose and NADPH that support biosynthesis and antioxidant defense. Our recent findings suggest that the p53-related protein TAp73 enhances the PPP flux. TAp73 stimulates the expression of glucose-6-phophate dehydrogenase (G6PD), the rate-limiting enzymes...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905063/ https://ncbi.nlm.nih.gov/pubmed/24270845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27267 |
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