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TAp73 enhances the pentose phosphate pathway and supports cell proliferation
TAp73 is a structural homologue of the pre-eminent tumor suppressor p53. However, unlike p53, TAp73 is rarely mutated, and instead is frequently over-expressed in human tumors. It remains unclear whether TAp73 affords an advantage to tumor cells and if so, what is the underlying mechanism. Here we s...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733810/ https://ncbi.nlm.nih.gov/pubmed/23811687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2789 |
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