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A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation

The pentose phosphate pathway (PPP) provides ribose and NADPH that support biosynthesis and antioxidant defense. Our recent findings suggest that the p53-related protein TAp73 enhances the PPP flux. TAp73 stimulates the expression of glucose-6-phophate dehydrogenase (G6PD), the rate-limiting enzymes...

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Autores principales: Jiang, Peng, Du, Wenjing, Yang, Xiaolu
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905063/
https://ncbi.nlm.nih.gov/pubmed/24270845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27267
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